Table 7.
Proteomic databases relevant to organelle analysis.
| Software & Website |
Type | Features | Organelles | Reference |
|---|---|---|---|---|
| LOCATE http://locate.imb.uq.edu.au/ | Human and murine subcellular protein localization database | Based entirely on experimental results, MemO (membrane protein prediction), subcellular localization via N-terminal myc tag, and indirect immunofluorescence, Location Proteome (proteins contained within a specific area of the cell based on fluorescence spectroscopy creating a localization tree) | Nucleus, plasma membrane, extracellular, mitochondria, ER, Golgi apparatus, lysosomes, endosomes, cytoplasmic vesicles, peroxisome, cytoskeleton | Sprenger, 2008262 |
| iLOC-EUK | Subcellular localization prediction tool for single- or multiple-location eukaryotic proteins | GO (Gene Ontology), SeqEvo (Sequential Evolution) descriptor, Multi-Label KNN (K-Nearest Neighbor) classifier, PseAAC (pseudo amino acid composition) | Acrosome, cell membrane, cell wall, centriole, chloroplast, cyanelle, cytoplasm, cytoskeleton, ER, endosome, extracellular, Golgi apparatus, hydrogenosome, lysosome, melanosome, microsome, mitochondrion, nucleus, peroxisome, spindle pole body, synapse, vacuole | Chou, 2011263 |
| Plant-mPLoc http://www.csbio.sjtu.edu.cn/bioinf/plant-multi/ | Plant subcellular protein localization prediction tool | GO (Gene Ontology), FunD (Functional Domain) descriptor, SeqEvo (Sequential Evolution) descriptor, OET-KNN (Optimized Evidence-Theoretic K Nearest Neighbor) prediction engine | Cell membrane, cell wall, chloroplast, cytoplasm, ER, Golgi apparatus, mitochondrion, nucleus, peroxisome, plastid, vacuole | Chou, 2010264 |
| PepTracker http://www.peptracker.com/ | Platform for visualization of the distribution of proteins over subcellular compartments | Storage of quantitative data from MaxQuant, visualization of the data for more efficient data mining, automated analysis of patterns and trends | Nucleus, nucleolus, cytoplasm | Boisvert, 2012265 |