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. Author manuscript; available in PMC: 2014 Apr 10.
Published in final edited form as: Chem Rev. 2013 Apr 10;113(4):2733–2811. doi: 10.1021/cr300354g

Table 7.

Proteomic databases relevant to organelle analysis.

Software &
Website
Type Features Organelles Reference
LOCATE http://locate.imb.uq.edu.au/ Human and murine subcellular protein localization database Based entirely on experimental results, MemO (membrane protein prediction), subcellular localization via N-terminal myc tag, and indirect immunofluorescence, Location Proteome (proteins contained within a specific area of the cell based on fluorescence spectroscopy creating a localization tree) Nucleus, plasma membrane, extracellular, mitochondria, ER, Golgi apparatus, lysosomes, endosomes, cytoplasmic vesicles, peroxisome, cytoskeleton Sprenger, 2008262
iLOC-EUK Subcellular localization prediction tool for single- or multiple-location eukaryotic proteins GO (Gene Ontology), SeqEvo (Sequential Evolution) descriptor, Multi-Label KNN (K-Nearest Neighbor) classifier, PseAAC (pseudo amino acid composition) Acrosome, cell membrane, cell wall, centriole, chloroplast, cyanelle, cytoplasm, cytoskeleton, ER, endosome, extracellular, Golgi apparatus, hydrogenosome, lysosome, melanosome, microsome, mitochondrion, nucleus, peroxisome, spindle pole body, synapse, vacuole Chou, 2011263
Plant-mPLoc http://www.csbio.sjtu.edu.cn/bioinf/plant-multi/ Plant subcellular protein localization prediction tool GO (Gene Ontology), FunD (Functional Domain) descriptor, SeqEvo (Sequential Evolution) descriptor, OET-KNN (Optimized Evidence-Theoretic K Nearest Neighbor) prediction engine Cell membrane, cell wall, chloroplast, cytoplasm, ER, Golgi apparatus, mitochondrion, nucleus, peroxisome, plastid, vacuole Chou, 2010264
PepTracker http://www.peptracker.com/ Platform for visualization of the distribution of proteins over subcellular compartments Storage of quantitative data from MaxQuant, visualization of the data for more efficient data mining, automated analysis of patterns and trends Nucleus, nucleolus, cytoplasm Boisvert, 2012265