Table 5.

Transcriptome profile of genes within reported AIS candidate loci

Candidate region	References	Candidate gene	Ref_Seq	Chromosomal Localization	Fold-Change
11q21–q22	Qiu et al. [30]	MMP13	NM_002427.2	11q22.2b	0.62
1p35	Montanaro et al. [15]	TINAGL1	NM_022164.1	1p35.2a	−1.05
		IFI6	NM_022872.2	1p35.3b	−0.84
		SESN2	NM_031459.3	1p35.3b	0.76
6q25.1	Wu et al. [31]	ULBP1	NM_025218.2	6q25.1b	0.9
19p13.3	Chan et al. [14]	CD70	NM_001252.3	19p13.3a	0.71
	Alden et al. [32]	MKNK2	NM_017572.2	19p13.3 h	0.93
12p13.31	Raggio et al. [33]	CD4	NM_000616.3	12p13.31d	−0.32
		NTF3	NM_002527.3	12p13.31e	0.89
17q25.3–qtel	Ocaka et al. [16]	ARL16	NM_001040025.1	17q25.3f	−0.27
9q31.2–q34.2	Ocaka et al. [16]	PTGS1	NM_080591.1	9q33.2b	−0.86
		OLFML2A	NM_182487.2	9q33.3a	0.96
Xq23–26.1	Justice et al. [34]	GRIA3	NM_000828.3	Xq25b	−0.56
		GPC4	NM_001448.2	Xq26.2b	0.62
		MGC16121	XM_001128419.1	Xq26.3a	0.68
17p11.2	Salehi et al. [35]	EPPB9	NM_015681.2	17p11.2e	−0.48
		SPECC1	NM_001033554.1	17p11.2d-p11.2c	−0.31
18q	Wise et al. [10]	LOC284293	XM_209104.2	18q21.33b	−0.32
		BCL2	NM_000633.2	18q21.33b	0.48
10q	Wise et al. [10]	DDIT4	NM_019058.2	10q22.1f	1.62
		DKK1	NM_012242.2	10q21.1a	−1.28
		EMX2	NM_004098.2	10q26.11a	−0.89
		SVIL	NM_003174.3	10p11.23b	1.01
6q	Wise et al. [10]	FAM162B	NM_001085480.1	6q22.2a	−0.9
		SMOC2	NM_022138.1	6q27d–q27e	1.03
3q13.3	Edery et al. [11]	COL8A1	NM_001850	3q12.1b–q12.1c	−0.97
		HCLS1	NM_005335.3	3q13.33c	−1.42
5q13	Edery et al. [11]	FOXD1	NM_004472.2	5q13.2c	0.57
		F2R	NM_001992.2	5q13.3d	1.04
		F2RL2	NM_004101.2	5q13.3d	0.97
		BHMT2	NM_017614.3	5q14.1c	0.68

The table presents a list of genes within AIS reported loci and their corresponding fold-changes. As revealed by microarray analysis