Table 2.
Items included in the questionnaire sent to the participants
| Based on the following criteria, success in PJI treatment should be defined as: | |
|---|---|
| Dimension A Infection eradication, characterized by: | No clinical failure (healed wound without fistula or drainage and painless joint) |
| Return to baseline (or to the normal level) of serologic markers (including C-reactive protein, erythrocyte sedimentation rate, white blood cells) | |
| No need for antibiotic suppression treatment | |
| No infection recurrence caused by the same organism strain | |
| No incident (new) infection with a different organism | |
| No concomitant PJI in other surgical site | |
| Dimension B No subsequent surgical intervention after reimplantation surgery, characterized by: | No reoperation attributable to infection |
| No revisions owing to aseptic causes in the proposed followup period (including aseptic loosening, instability, stiffness) | |
| No radical surgeries after reimplantation (including: lower limb amputation, hip/knee arthrodesis, hip resection arthroplasty) | |
| Dimension C No presence of PJI-related morbidity or mortality, characterized by: | No death caused by a condition directly linked to PJI (including sepsis, necrotizing fasciitis). |
| No death in a hospitalization owing to treatment of PJI, by causes not directly linked with PJI (including myocardial infarction, stroke, pneumonia) | |
| Hospital length of stay less than 3 months/year during treatment of PJI | |
| No medical complications associated with PJI intravenous or local antibiotic treatment (including systemic toxicity, renal insufficiency, peripherally inserted central catheter line complications) | |
| Dimension D Maintenance of functional level after PJI treatment, characterized by: | Equal or better functional status than before the index arthroplasty (using any functional scale) |
| Equal or better functional status than before the diagnosis of PJI (in patient with formerly well-functioning arthroplasty), using any functional scale | |
| Functional improvement equal or better than the minimal clinical important difference described for the used score or functional scale | |
| Patient satisfaction with the achieved outcome (binary score: satisfied versus not satisfied) | |
| Absence of psychiatric comorbidity (or deterioration of previous disease) caused by PJI or its treatment | |
| Dimension E Definition of early results after PJI treatment (regarding peer-reviewed publications) | 1 year after PJI definitive surgery (last surgery performed for PJI) |
| 18 months after definitive surgery | |
| 2 years after definitive surgery | |
| Dimension F Definition of midterm results after PJI treatment (regarding peer-reviewed publications) | 3 years after definitive surgery |
| 4 years after definitive surgery | |
| 5 years after definitive surgery | |
| Dimension G Definition of long-term results after PJI treatment (regarding peer-reviewed publications) | Greater than 5 years after definitive surgery |
| 10 years or more after definitive surgery | |
PJI = periprosthetic joint infection.