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. Author manuscript; available in PMC: 2013 Jun 8.
Published in final edited form as: J Inorg Biochem. 2012 Oct 15;118:83–93. doi: 10.1016/j.jinorgbio.2012.10.006

Fig. 4.

Fig. 4

Time response experiment using C1 and C2 in human breast cancer MDA-MB-231 cells. MDA-MB-231 cells were treated with 20 μM of C1 and C2 for the indicated hours. (A) Kinetic studies on the inhibition of CT-like activity. (B) Western blottinganalysis using antibodies to proteasome target proteins (Bax and IκB-α), XIAP, and PARP. (C) Cellular morphological changes visualized by phase-contrast imaging.