Table 2.
Mortality rate ratios for age at natural menopause (N=11,212) Black Women’s Health Study, 1995-2008
| Age at natural menopause, years |
Deaths | Person- years |
Multivariate MRRa (95% CI) |
|---|---|---|---|
| All | |||
| <40 | 50 | 5,832 | 1.34 (0.96, 1.84) |
| 40-44 | 95 | 10,660 | 1.33 (1.04, 1.70) |
| 45-49 | 197 | 29,320 | 1.04 (0.86, 1.26) |
| 50-54 | 253 | 36,096 | 1.00 (ref) |
| ≥55 | 97 | 9,921 | 1.02 (0.80, 1.31) |
| P-value, test for trend | 0.04 | ||
| 1925-1934 | |||
| <40 | 13 | 539 | 1.49 (0.80, 2.79) |
| 40-44 | 30 | 1361 | 1.41 (0.90, 2.21) |
| 45-49 | 54 | 3017 | 0.93 (0.65, 1.34) |
| 50-54 | 81 | 5319 | 1.00 (ref) |
| >55 | 67 | 3360 | 1.41 (1.01, 1.98) |
| P-value, test for trend | 0.85 | ||
| 1935-1944 | |||
| <40 | 17 | 1118 | 1.32 (0.77, 2.27) |
| 40-44 | 33 | 2784 | 1.22 (0.81, 1.82) |
| 45-49 | 79 | 9644 | 0.98 (0.73, 1.31) |
| 50-54 | 122 | 16384 | 1.00 (ref) |
| >55 | 27 | 4945 | 0.70 (0.46, 1.08) |
| P-value, test for trend | 0.05 | ||
| 1945-1973b | |||
| <40 | 20 | 4175 | 1.16 (0.59, 2.6) |
| 40-44 | 32 | 6515 | 1.25 (0.75, 2.11) |
| 45-49 | 64 | 16659 | 1.08 (0.72, 1.61) |
| 50-54 | 50 | 14393 | 1.00 (ref) |
| ≥55 | 3 | 1617 | 0.47 (0.14, 1.54) |
| P-value, test for trend | 0.26 |
MRR= mortality rate ratio; CI = confidence interval.
a
Model adjusts for age (1-year intervals) and time period (2-year intervals), education, marital status, BMI, smoking status, pack years of smoking, alcohol consumption, vigorous physical activity, vegetables/fruit dietary pattern, meats/fried food dietary pattern, and reproductive factors, age at menarche, parity, age at first birth, oral contraceptive use, lactation duration, and unilateral oophorectomy.
b
Birth cohorts of 1955-1964 and 1965-1973 were collapsed with 1945-1954 due to small numbers.