Table 3.
Cause-specific mortality rate ratios for age at natural menopause (N=11,212). Black Women’s Health Study, 1995-2008
| Age at natural menopause, years |
Cancer mortality |
Cardiovascular mortality |
Other-cause mortality |
||||
|---|---|---|---|---|---|---|---|
| Person- years |
Deaths | Multivariable MRRa (95% CI) |
Deaths | Multivariable MRRa (95% CI) |
Deaths | Multivariable MRRa (95% CI) |
|
| < 40 | 5,832 | 13 | 1.23 (0.69, 2.23) | 15 | 1.28 (0.70, 2.36) | 22 | 1.46 (0.85, 2.50) |
| 40-44 | 10,660 | 35 | 1.36 (0.91, 2.05) | 24 | 1.18 (0.73, 1.90) | 36 | 1.44 (0.95, 2.18) |
| 45-49 | 29,320 | 69 | 1.02 (0.75, 1.40) | 60 | 1.09 (0.76, 1.56) | 68 | 1.02 (0.73, 1.43) |
| 50-54 | 36,096 | 100 | 1.00 (ref) | 70 | 1.00 (ref) | 83 | 1.00 (ref) |
| ≥55 | 9,921 | 44 | 1.20 (0.83, 1.74) | 30 | 1.01 (0.64, 1.59) | 23 | 0.81 (0.51, 1.30) |
| P-value, test for trend | 0.56 | 0.37 | 0.02 | ||||
MRR= mortality rate ratio; CI = confidence interval.
a
Fully adjusted model, including age (1-year intervals), time period (2-year intervals), education years, marital status, BMI, smoking status, pack years of smoking, alcohol consumption, vigorous physical activity, vegetables/fruit dietary pattern, and meats/fried food dietary pattern, age at menarche, parity, age at first birth, oral contraceptive use, lactation, and unilateral oophorectomy