Table 2.
Associations of telomere length with anthropometric measurements, the Shanghai Women’s Health Study
| Anthropometric variables | Relative Telomere Length | ||||
|---|---|---|---|---|---|
| N | aMean (95% CIs) | bMean (95% CIs) | cRatio (95% CIs) | P | |
| Weight (Kg) | |||||
| Q1 (< 54) | 754 | 0.945(0.933,0.958) | 0.946 (0.933, 0.959) | Ref. (1.00) | |
| Q2 (54 – 59.9) | 668 | 0.937(0.923,0.950) | 0.938 (0.925, 0.952) | 0.992(0.972,1.012) | 0.747 |
| Q3 (60–65.9) | 726 | 0.929(0.917,0.943) | 0.929 (0.917, 0.942) | 0.982(0.963,1.001) | 0.170 |
| Q4 (> 66.0) | 772 | 0.924 (0.913, 0.938) | 0.924(0.911,0.936) | 0.976 (0.957, 0.995) | 0.043 |
| P for trend | 0.019 | 0.010 | |||
| Height (m) | |||||
| Q1(<1.54) | 737 | 0.928(0.915,0.941) | 0.927(0.914,0.941) | 0.973 (0.954, 0.993) | 0.022 |
| Q2 (1.54–1.57) | 728 | 0.933 (0.920, 0.946) | 0.933(0.921,0.946) | 0.979(0.961,0.999) | 0.090 |
| Q3 (1.58–1.60) | 693 | 0.952(0.939,0.966) | 0.953 (0.940, 0.966) | Ref. (1.00) | |
| Q4(>1.60) | 754 | 0.924(0.912,0.938) | 0.926 (0.913, 0.939) | 0.971(0.952,0.991) | 0.011 |
| P for trend | 0.842 | 0.675 | |||
| Waist circumference (cm) | |||||
| Normal (< 80) | 1,547 | 0.942(0.933,0.951) | 0.943 (0.934, 0.953) | Ref. (1.00) | |
| Action level 1 (80–87.9) | 825 | 0.929(0.917,0.941) | 0.929(0.917,0.941) | 0.983(0.968,1.000) | 0.116 |
| Action level 2 (≥ 88) | 540 | 0.920 (0.905, 0.935) | 0.917 (0.902, 0.933) | 0.971(0.952,0.990) | 0.014 |
| P for trend | 0.019 | 0.004 | |||
| Hip circumference (cm) | |||||
| Ql(≤91.0) | 705 | 0.937 (0.924, 0.950) | 0.938 (0.925, 0.952) | Ref. (1.00) | |
| Q2 (91.1–96.5) | 681 | 0.942 (0.929, 0.956) | 0.943 (0.930, 0.956) | 1.005(0.986,1.026) | 0.922 |
| Q3 (96.6–102) | 640 | 0.939 (0.927, 0.952) | 0.938(0.926,0.951) | 0.999(0.980,1.019) | 1.000 |
| Q4 (> 102) | 740 | 0.917(0.903,0.930) | 0.916 (0.902, 0.929) | 0.974 (0.955, 0.994) | 0.053 |
| P for trend | 0.044 | 0.026 | |||
| BMI (Kg/m2) | |||||
| < 18.5 | 76 | 0.910 (0.872, 0.949) | 0.912 (0.874, 0.952) | 0.966(0.925,1.010) | 0.331 |
| 18.5–24.9 | 1,643 | 0.942(0.934,0.951) | 0.943 (0.935, 0.952) | Ref. (1.00) | |
| 25–29.9 | 991 | 0.929 (0.918, 0.940) | 0.928(0.917,0.939) | 0.983 (0.969, 0.998) | 0.102 |
| ≥30 | 201 | 0.903 (0.879, 0.927) | 0.899 (0.875, 0.923) | 0.951(0.925,0.979) | 0.004 |
| P for trend | 0.014 | 0.005 | |||
| WHR | |||||
| Q1(< 0.779) | 726 | 0.938(0.925,0.952) | 0.939 (0.926, 0.953) | Ref. (1.00) | |
| Q2 (0.779–0.813) | 725 | 0.939 (0.926, 0.952) | 0.940 (0.927, 0.953) | 1.001(0.980,1.020) | 1.000 |
| Q3 (0.814–0.850) | 740 | 0.933 (0.926, 0.945) | 0.932 (0.920, 0.945) | 0.992(0.973,1.012) | 0.797 |
| Q4 (> 0.850) | 720 | 0.926(0.913,0.940) | 0.925 (0.912, 0.939) | 0.984(0.965,1.005) | 0.349 |
| P for trend | 0.167 | 0.116 | |||
| WHtR | |||||
| Q1(< 0.461) | 730 | 0.943 (0.929, 0.956) | 0.944(0.931,0.958) | Ref. (1.00) | |
| Q2 (0.461–0.50) | 728 | 0.945(0.932,0.959) | 0.947 (0.934, 0.961) | 1.004(0.983,1.024) | 0.988 |
| Q3 (0.51–0.544) | 725 | 0.928(0.915,0.941) | 0.928(0.915,0.941) | 0.983(0.963,1.003) | 0.231 |
| Q4 (> 0.544) | 792 | 0.921(0.908,0.935) | 0.918(0.904,0.932) | 0.972 (0.952, 0.993) | 0.033 |
| P for trend | 0.013 | 0.004 | |||
a
Adjusted for age at blood collection and education.
b
Multiple adjustment for age at blood collection, education, cigarette smoking status, regular alcohol consumption, cancer case/control status, and comorbidities.
c
Derived from the results with multiple adjustment.