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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Nat Med. 2013 May 26;19(6):722–729. doi: 10.1038/nm.3190

Figure 3.

Figure 3

IKKα’s function and NF-κB pathway. (a–c) Effects of knockdown of NF-κB pathway on HCV infection. Values represent the means ± s.d., n = 3. **, P < 0.01. (d) Effects of NF-κB silencing on HCV core-associated LD contents and 3’UTR-induced LD formation. (e) Huh7.5.1 cells were treated with indicated siRNAs, and then transfected with control or HA-IKKα plasmid before infection with HCV. Extracellular HCV RNA levels were subsequently measured and normalized to samples treated with siNT and control plasmid. (f) Huh7.5.1 cells were incubated with IL-1β (0.1 µg ml−1) or LTα/β (0.1 µg ml−1) for 30 min, and stained for LD contents and IKKα. Scale bars represent 20 µm.