Table 1.

Enzymes and factors involved in antioxidant defense in the skin.

Antioxidants	Examples	Target
Enzymatic	Superoxide dismutase	Superoxide
	Catalase	Hydrogen peroxide
	Glutathione peroxidase	Hydrogen peroxide, lipid peroxides
	Peroxiredoxin	Hydrogen peroxide
	Heme oxygenase	Heme
Non-enzymatic	Bilirubin	Lipid peroxides
	Vitamin C	Superoxide, hydroxyl radical, reactive nitrogen species, trace metals
	Vitamin E	Lipid peroxides
Metal-binding proteins	Ferritin	Free iron