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Effect of SMP30 deficiency on generation of superoxide and activity of NADPH oxidase in cardiac myocytes under electrical stimulation. Generation of superoxide (A) was measured by HPLC. NADPH oxidase activity was measured by lucigenin luminescence; (B) The levels of superoxide and NADPH oxidase activity were greater in SMP30 KO mice compared to WT mice under electrical stimulation. Values were expressed as the mean ± S.E.M. * p < 0.01 vs. without agents. n = 8, each.
