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. 2013 May 17;14(5):10369–10382. doi: 10.3390/ijms140510369

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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LC depressed Col-I deposition via depletion of peritoneal M2. Values were expressed as the mean ± SD. (A) The overexpression of Col-I induced by Lactate-4.25% dialysate was evidently downregulated by LC treatment measured by Western blotting; (B) The relative protein level of Col-I normalized by GAPDH; (C) The mRNA level of Col-I was depressed by LC treatment; (D) Immunofluorescence staining of Col-I in the four groups. Blue corresponds to nuclear staining; green corresponds to Col-I staining. ^#p < 0.05, vs. NC and LC group.