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. 2013 May 21;14(5):10626–10660. doi: 10.3390/ijms140510626

Table 4.

The significant gene ontology molecular functions in pigs.

Name Description Probe Genes
[GO:0017076] purine nucleotide binding 91 91
[GO:0003676] nucleic acid binding 88 88
[GO:0032555] purine ribonucleotide binding 81 81
[GO:0004872] receptor activity 75 75
[GO:0004690] cyclic nucleotide-dependent protein kinase activity 68 68
[GO:0004691] cAMP-dependent protein kinase activity 67 67
[GO:0016491] oxidoreductase activity 67 67
[GO:0008270] zinc ion binding 64 64
[GO:0030554] adenyl nucleotide binding 63 63
[GO:0005102] receptor binding 57 57
[GO:0032559] adenyl ribonucleotide binding 53 53
[GO:0005215] transporter activity 52 52
[GO:0008233] peptidase activity 46 46
[GO:0070011] peptidase activity, acting on l-amino acid peptides 43 43
[GO:0003677] DNA binding 43 43
[GO:0004888] transmembrane receptor activity 40 40
[GO:0005509] calcium ion binding 39 39
[GO:0022892] substrate-specific transporter activity 39 39
[GO:0004687] myosin light chain kinase activity 38 38
[GO:0030528] transcription regulator activity 37 37
[GO:0022857] transmembrane transporter activity 36 36
[GO:0022891] substrate-specific transmembrane transporter activity 35 35
[GO:0030234] enzyme regulator activity 35 35
[GO:0005506] iron ion binding 33 33
[GO:0004175] endopeptidase activity 33 33
[GO:0003700] transcription factor activity 32 32
[GO:0015075] ion transmembrane transporter activity 30 30
[GO:0019001] guanyl nucleotide binding 28 28
[GO:0005198] structural molecule activity 28 28
[GO:0004857] enzyme inhibitor activity 26 26
[GO:0016788] hydrolase activity, acting on ester bonds 26 26
[GO:0008324] cation transmembrane transporter activity 25 25
[GO:0009055] electron carrier activity 24 24
[GO:0004930] G-protein coupled receptor activity 24 24
[GO:0003723] RNA binding 23 23
[GO:0005126] cytokine receptor binding 22 22
[GO:0016874] ligase activity 22 22
[GO:0048037] cofactor binding 20 20
[GO:0016817] hydrolase activity, acting on acid anhydrides 19 19
[GO:0003735] structural constituent of ribosome 19 19
[GO:0005125] cytokine activity 18 18
[GO:0030414] peptidase inhibitor activity 18 18
[GO:0050662] coenzyme binding 17 17
[GO:0016757] transferase activity, transferring glycosyl groups 17 17
[GO:0030246] carbohydrate binding 17 17
[GO:0008092] cytoskeletal protein binding 16 16
[GO:0022890] inorganic cation transmembrane transporter activity 16 16
[GO:0016746] transferase activity, transferring acyl groups 16 16
[GO:0016879] ligase activity, forming carbon-nitrogen bonds 16 16
[GO:0000287] magnesium ion binding 15 15
[GO:0008237] metallopeptidase activity 15 15
[GO:0016614] oxidoreductase activity, acting on CH–OH group of donors 15 15
[GO:0022804] active transmembrane transporter activity 15 15
[GO:0019955] cytokine binding 14 14
[GO:0017171] serine hydrolase activity 14 14
[GO:0046906] tetrapyrrole binding 14 14
[GO:0016616] oxidoreductase activity, acting on the CH–OH group of donors, NAD or NADP as acceptor 14 14
[GO:0016747] transferase activity, transferring acyl groups other than amino-acyl groups 14 14
[GO:0008528] peptide receptor activity, G-protein coupled 14 14
[GO:0003779] actin binding 14 14
[GO:0004252] serine-type endopeptidase activity 13 13
[GO:0016705] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 13 13
[GO:0004497] monooxygenase activity 12 12
[GO:0042578] phosphoric ester hydrolase activity 12 12
[GO:0008234] cysteine-type peptidase activity 11 11
[GO:0046873] metal ion transmembrane transporter activity 11 11
[GO:0008289] lipid binding 11 11
[GO:0016791] phosphatase activity 11 11
[GO:0050660] FAD binding 10 10
[GO:0015078] hydrogen ion transmembrane transporter activity 10 10
[GO:0016758] transferase activity, transferring hexosyl groups 10 10
[GO:0004867] serine-type endopeptidase inhibitor activity 10 10
[GO:0004428] inositol or phosphatidylinositol kinase activity 10 10
[GO:0016798] hydrolase activity, acting on glycosyl bonds 10 10
[GO:0005516] calmodulin binding 9 9
[GO:0016810] hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9 9
[GO:0042623] ATPase activity, coupled 9 9
[GO:0001871] pattern binding 9 9
[GO:0016776] phosphotransferase activity, phosphate group as acceptor 9 9
[GO:0005179] hormone activity 9 9
[GO:0070851] growth factor receptor binding 9 9
[GO:0004197] cysteine-type endopeptidase activity 9 9
[GO:0005057] receptor signaling protein activity 9 9
[GO:0004950] chemokine receptor activity 9 9
[GO:0004222] metalloendopeptidase activity 9 9
[GO:0043565] sequence-specific DNA binding 9 9
[GO:0005216] ion channel activity 8 8
[GO:0016853] isomerase activity 8 8
[GO:0000826] inositol pyrophosphate synthase activity 8 8
[GO:0019842] vitamin binding 8 8
[GO:0005539] glycosaminoglycan binding 8 8
[GO:0005529] sugar binding 8 8
[GO:0005066] transmembrane receptor protein tyrosine kinase signaling protein activity 8 8
[GO:0020037] heme binding 8 8
[GO:0004356] glutamate-ammonia ligase activity 8 8
[GO:0005507] copper ion binding 7 7
[GO:0016209] antioxidant activity 7 7
[GO:0008238] exopeptidase activity 7 7
[GO:0008009] chemokine activity 7 7
[GO:0016860] intramolecular oxidoreductase activity 7 7
[GO:0004721] phosphoprotein phosphatase activity 7 7
[GO:0015291] secondary active transmembrane transporter activity 7 7
[GO:0016563] transcription activator activity 6 6
[GO:0005244] voltage-gated ion channel activity 6 6
[GO:0008201] heparin binding 6 6
[GO:0031420] alkali metal ion binding 6 6
[GO:0046983] protein dimerization activity 6 6
[GO:0015082] di-, tri-valent inorganic cation transmembrane transporter activity 6 6
[GO:0004312] fatty-acid synthase activity 6 6
[GO:0042802] identical protein binding 6 6
[GO:0016684] oxidoreductase activity, acting on peroxide as acceptor 6 6
[GO:0016829] lyase activity 5 5
[GO:0008047] enzyme activator activity 5 5
[GO:0003924] GTPase activity 5 5
[GO:0004091] carboxylesterase activity 5 5
[GO:0015399] primary active transmembrane transporter activity 5 5
[GO:0005261] cation channel activity 5 5
[GO:0019904] protein domain specific binding 5 5
[GO:0004694] eukaryotic translation initiation factor 2alpha kinase activity 5 5
[GO:0016627] oxidoreductase activity, acting on the CH–CH group of donors 5 5
[GO:0031406] carboxylic acid binding 5 5
[GO:0042803] protein homodimerization activity 5 5
[GO:0004518] nuclease activity 5 5
[GO:0019899] enzyme binding 5 5
[GO:0003774] motor activity 5 5
[GO:0008430] selenium binding 5 5
[GO:0004725] protein tyrosine phosphatase activity 5 5
[GO:0015293] symporter activity 5 5
[GO:0004713] protein tyrosine kinase activity 5 5
[GO:0046915] transition metal ion transmembrane transporter activity 4 4
[GO:0008135] translation factor activity, nucleic acid binding 4 4
[GO:0008134] transcription factor binding 4 4
[GO:0010857] calcium-dependent protein kinase activity 4 4
[GO:0050661] NADP or NADPH binding 4 4
[GO:0060589] nucleoside-triphosphatase regulator activity 4 4
[GO:0008373] sialyltransferase activity 4 4
[GO:0004896] cytokine receptor activity 4 4
[GO:0008083] growth factor activity 4 4
[GO:0016709] oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 4 4
[GO:0004576] oligosaccharyl transferase activity 4 4
[GO:0008509] anion transmembrane transporter activity 4 4
[GO:0051540] metal cluster binding 4 4
[GO:0004177] aminopeptidase activity 4 4
[GO:0016765] transferase activity, transferring alkyl or aryl (other than methyl) groups 4 4
[GO:0015929] hexosaminidase activity 4 4
[GO:0016741] transferase activity, transferring one-carbon groups 4 4
[GO:0004129] cytochrome-c oxidase activity 4 4
[GO:0004521] endoribonuclease activity 4 4
[GO:0051287] NAD or NADH binding 3 3
[GO:0005385] zinc ion transmembrane transporter activity 3 3
[GO:0004774] succinate-CoA ligase activity 3 3
[GO:0004090] carbonyl reductase (NADPH) activity 3 3
[GO:0005249] voltage-gated potassium channel activity 3 3
[GO:0008757] S-adenosylmethionine-dependent methyltransferase activity 3 3
[GO:0005160] transforming growth factor beta receptor binding 3 3
[GO:0008235] metalloexopeptidase activity 3 3
[GO:0005275] amine transmembrane transporter activity 3 3
[GO:0019840] isoprenoid binding 3 3
[GO:0019838] growth factor binding 3 3
[GO:0005128] erythropoietin receptor binding 3 3
[GO:0016801] hydrolase activity, acting on ether bonds 3 3
[GO:0016701] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3 3
[GO:0003712] transcription cofactor activity 3 3
[GO:0015144] carbohydrate transmembrane transporter activity 3 3
[GO:0003995] acyl-CoA dehydrogenase activity 3 3
[GO:0004869] cysteine-type endopeptidase inhibitor activity 3 3
[GO:0031402] sodium ion binding 3 3
[GO:0019888] protein phosphatase regulator activity 3 3
[GO:0016651] oxidoreductase activity, acting on NADH or NADPH 3 3
[GO:0004180] carboxypeptidase activity 3 3
[GO:0030695] GTPase regulator activity 3 3
[GO:0010181] FMN binding 3 3
[GO:0003743] translation initiation factor activity 3 3
[GO:0016861] intramolecular oxidoreductase activity, interconverting aldoses and ketoses 3 3
[GO:0004522] pancreatic ribonuclease activity 3 3
[GO:0015294] solute:cation symporter activity 3 3
[GO:0016790] thiolester hydrolase activity 3 3
[GO:0008026] ATP-dependent helicase activity 3 3
[GO:0030145] manganese ion binding 3 3
[GO:0008417] fucosyltransferase activity 3 3
[GO:0008194] UDP-glycosyltransferase activity 3 3
[GO:0008199] ferric iron binding 3 3