Table 2.

Clinical outcomes of hematopoietic cell transplant recipients with influenza infection according to corticosteroid treatment

	Corticosteroid treatment
Clinical outcome	None N=63	Low dose* N=43†	High dose* N=37	All patients N=143
Site of influenza infection
URI only	47 (75)	36 (84)	28 (76)	111 (78)
URI followed by LRD	4 (6)	2 (5)	2 (5)	8 (6)
LRD at diagnosis	12 (19)	5 (12)	7 (19)	24 (17)
Hypoxemia	16 (25)	10 (23)	7 (19)	33 (23)
Mechanical ventilation	9 (14)	3 (7)	1 (3)	13 (9)
Influenza-associated deaths‡	6 (10)	2 (5)	4 (11)	12 (8)
Deaths‡	7 (11)	5 (12)	5 (14)	17 (12)
Prolonged shedding¶	11 (25)	3 (16)	11 (46)	25 (29)

LRD indicates lower respiratory tract disease; URI, upper respiratory tract infection.

Note: Data are number (%) of patients.

^*Low dose: < 1 mg/kg or oral beclomethasone diproprionate. High dose: ≥ 1 mg/kg.

^†Six patients received oral beclomethasone diproprionate (BDP) only and 37 patients received systemic corticosteroid at dosage < 1 mg/kg with or without oral BDP.

^‡During the first 42 days following influenza diagnosis.

^¶Defined as viral excretion > 14 days. Only 87 patients with available data for this analysis