Table 2.
Risk of plasma cell neoplasms according to demographic characteristics and transplanted organ
Characteristic | N | Incidence* | SIR | 95% lower limit | 95% upper limit | P-value for heterogeneity in SIRs |
---|---|---|---|---|---|---|
Sex | 0.25 | |||||
Female | 36 | 9.9 | 1.55 | 1.09 | 2.15 | |
Male | 104 | 18.9 | 1.90 | 1.55 | 2.30 | |
Age at transplant, years | 0.03 | |||||
0–34 | 7 | 3.0 | 8.19 | 3.29 | 16.87 | |
35–49 | 30 | 9.8 | 2.36 | 1.59 | 3.37 | |
50–64 | 79 | 25.4 | 1.69 | 1.33 | 2.10 | |
65+ | 24 | 40.6 | 1.37 | 0.88 | 2.04 | |
Race/ethnicity | 0.04 | |||||
White | 97 | 16.4 | 2.01 | 1.63 | 2.45 | |
Black | 23 | 17.2 | 1.25 | 0.79 | 1.88 | |
Hispanic | 13 | 9.6 | 1.43 | 0.76 | 2.45 | |
Asian/Pacific Islander | 7 | 14.0 | 3.19 | 1.28 | 6.57 | |
Transplanted organ | 0.25 | |||||
Kidney | 82 | 15.6 | 1.88 | 1.50 | 2.34 | |
Liver | 22 | 10.9 | 1.29 | 0.81 | 1.96 | |
Heart | 30 | 27.2 | 2.27 | 1.53 | 3.25 | |
Lung | 2 | 7.2 | 0.86 | 0.10 | 3.09 | |
Other | 4 | 8.4 | 2.26 | 0.61 | 5.77 | |
HLA mismatch† | 0.26 | |||||
0–2 | 28 | 15.2 | 2.10 | 1.39 | 3.03 | |
3–4 | 44 | 13.2 | 1.51 | 1.10 | 2.03 | |
5–6 | 51 | 18.8 | 2.03 | 1.51 | 2.67 |
Notes
Abbreviations: SIR standardized incidence ratio
Incidence rate is per 100,000 person-years.
Subjects with missing data on HLA mismatch were excluded from this analysis.