Table 3.
Relative risk of pancreatic adenocarcinoma two or more years after first primary cancer, stratified by age at diagnosis of first primary cancer.
| 20-49 years | 50-64 years | 65+ years | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Site | Obs | Exp | RR | CI | Obs | Exp | RR | CI | Obs | Exp | RR | CI |
| Digestive System | ||||||||||||
| Esophagus | 1 | 0.27 | 3.74 | 0.09-20.85 | 5 | 2.68 | 1.87 | 0.61-4.35 | 2 | 3.59 | 0.56 | 0.07-2.02 |
| Stomach | 2 | 1.52 | 1.32 | 0.16-4.75 | 19 | 10.13 | 1.88 | 1.13-2.93 | 32 | 17.85 | 1.79 | 1.23-2.53 |
| Small Intestine | 2 | 0.77 | 2.59 | 0.31-9.36 | 2 | 3.5 | 0.57 | 0.07-2.07 | 5 | 4.21 | 1.19 | 0.39-2.77 |
| Ascending Colon | 7 | 1.51 | 4.62 | 1.86-9.52 | 14 | 14.04 | 1 | 0.55-1.67 | 48 | 36.78 | 1.31 | 0.96-1.73 |
| Hepatic Flexure | 3 | 0.55 | 5.42 | 1.12-15.84 | 10 | 4.45 | 2.25 | 1.08-4.13 | 19 | 10.78 | 1.76 | 1.06-2.75 |
| Transverse Colon | 2 | 1.4 | 1.43 | 0.17-5.16 | 17 | 10.18 | 1.67 | 0.97-2.67 | 27 | 21.83 | 1.24 | 0.82-1.8 |
| Descending Colon | 1 | 1.3 | 0.77 | 0.02-4.29 | 9 | 11.73 | 0.77 | 0.35-1.46 | 20 | 17.24 | 1.16 | 0.71-1.79 |
| Rectum | 7 | 4.84 | 1.45 | 0.58-2.98 | 37 | 41.78 | 0.89 | 0.62-1.22 | 38 | 58.34 | 0.65 | 0.46-0.89 |
| Liver, Gallbladder, Intrahep Bile Duct and Other Biliary | 5 | 0.38 | 13.14 | 4.27-30.66 | 1 | 2.73 | 0.37 | 0.01-2.04 | 11 | 4.68 | 2.35 | 1.17-4.20 |
| Respiratory System | ||||||||||||
| Lung and Bronchus | 9 | 6.65 | 1.35 | 0.62-2.57 | 81 | 55.42 | 1.46 | 1.16-1.82 | 73 | 67.77 | 1.08 | 0.84-1.35 |
| Skin and Soft Tissue | ||||||||||||
| Melanoma of the Skin | 31 | 27.92 | 1.11 | 0.75-1.58 | 60 | 64.41 | 0.93 | 0.71-1.20 | 53 | 54.68 | 0.97 | 0.73-1.27 |
| Female Breast | 112 | 84.76 | 1.32 | 1.09-1.59 | 305 | 305.11 | 1 | 0.89-1.12 | 355 | 364.04 | 0.98 | 0.88-1.08 |
| Female Genital System | ||||||||||||
| Cervix Uteri | 23 | 14.3 | 1.61 | 1.02-2.41 | 23 | 19.69 | 1.17 | 0.74-1.75 | 14 | 12.16 | 1.15 | 0.60-1.93 |
| Corpus Uteri | 18 | 15.19 | 1.19 | 0.70-1.87 | 120 | 133.31 | 0.9 | 0.75-1.08 | 124 | 100.58 | 1.23 | 1.03-1.47 |
| Ovary | 7 | 6.7 | 1.04 | 0.42-2.15 | 25 | 19.82 | 1.26 | 0.82-1.86 | 16 | 15.66 | 1.02 | 0.58-1.66 |
| Male Genital System | ||||||||||||
| Prostate | 4 | 4.42 | 0.90 | 0.25-2.31 | 223 | 245.72 | 0.91 | 0.79-1.03 | 694 | 671.78 | 1.03 | 0.96-1.11 |
| Testis | 27 | 9.71 | 2.78 | 1.83-4.05 | 7 | 3.96 | 1.77 | 0.71-3.64 | 1 | 0.83 | 1.20 | 0.03-6.68 |
| Urinary System | ||||||||||||
| Kidney and Renal Pelvis | 7 | 6.85 | 1.02 | 0.41-2.11 | 41 | 34.59 | 1.19 | 0.85-1.61 | 49 | 37.67 | 1.30 | 0.96-1.72 |
| Urinary Bladder | 15 | 13.59 | 1.10 | 0.62-1.82 | 122 | 98.57 | 1.24 | 1.03-1.48 | 154 | 151.63 | 1.02 | 0.86-1.19 |
| Endocrine System | ||||||||||||
| Thyroid | 11 | 17.02 | 0.65 | 0.32-1.16 | 20 | 23.37 | 0.86 | 0.52-1.32 | 13 | 13.38 | 0.97 | 0.52-1.66 |
| Adrenal Gland | 0 | 0.14 | 0.00 | 0.00-25.66 | 2 | 0.34 | 5.94 | 0.72-21.44 | 0 | 0.21 | 0 | 0.00-17.34 |
| Head and Neck | ||||||||||||
| Pharynx | 1 | 1.13 | 0.89 | 0.02-4.94 | 11 | 4.88 | 2.26 | 1.13-4.04 | 5 | 3.86 | 1.30 | 0.42-3.02 |
| All Lymphatic and Hematopoietic Diseases | 36 | 19.72 | 1.83 | 1.28-2.53 | 84 | 75.56 | 1.11 | 0.89-1.38 | 98 | 102.74 | 0.95 | 0.77-1.16 |
| Brain and Other Nervous System | 2 | 2.25 | 0.89 | 0.11-3.22 | 2 | 2.63 | 0.76 | 0.09-2.75 | 0 | 1.4 | 0 | 0.00-2.63 |
Table 3 legend: All statistics represent values for combined male and female group. SIR (O/E) in bold are statistically significant at p < 0.05. Confidence intervals are 95%.