TABLE 3.
Baseline and follow-up characteristics of case participants included in the follow-up study, Queensland study of Melanoma: Environmental and Genetics Associations (Q-MEGA), Queensland, Australia, 1987–2005
| Variable | QFMP* (n=1,619) | Children (n=50) | Adolescents (n=142) | Men Over 50 (n=71) | Q-MEGA*† (n=1,894) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| No. | % | No. | % | No. | % | No. | % | No. | % | |
| Sex | ||||||||||
| Female | 910 | 56.2 | 23 | 46.0 | 75 | 52.8 | 0 | 0.0 | 1,005 | 53.1 |
| Male | 709 | 43.8 | 27 | 54.0 | 67 | 47.2 | 71 | 100.0 | 889 | 46.9 |
| Age at inclusion / interview | ||||||||||
| Mean (SD) | 47.5 (14.9) | 17.1 (2.4) | 23.3 (2.6) | 62.7 (8.1) | 58.9 (16.5) | |||||
| Median | 47.7 | 16.9 | 23.3 | 63.5 | 59.9 | |||||
| Age at first diagnosis of CMM* | ||||||||||
| Mean (SD) | 43.7 (15.1) | 13.5 (1.5) | 17.8 (1.5) | 62.2 (8.0) | 43.2 (16.3) | |||||
| Median | 43.7 | 13.9 | 18.0 | 62.9 | 43.6 | |||||
| Anatomical site of CMM* | ||||||||||
| Head and neck | 200 | 12.3 | 7 | 14.0 | 12 | 8.5 | 10 | 14.1 | 239 | 12.6 |
| Trunk | 534 | 33.0 | 28 | 56.0 | 69 | 48.6 | 36 | 50.7 | 640 | 33.8 |
| Upper limbs | 353 | 21.8 | 12 | 24.0 | 30 | 21.1 | 18 | 25.4 | 425 | 22.5 |
| Lower limbs | 435 | 26.9 | 3 | 6.0 | 31 | 21.8 | 7 | 9.8 | 481 | 25.4 |
| Unknown | 97 | 6.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 109 | 5.7 |
| Breslow thickness of CMM* | ||||||||||
| Melanoma in situ | 392 | 24.2 | 13 | 26.0 | 35 | 24.7 | 0 | 0.0 | 448 | 23.7 |
| < 0.3 mm | 134 | 8.3 | 3 | 6.0 | 8 | 5.6 | 7 | 9.9 | 156 | 8.2 |
| 0.3 – 0.5 mm | 449 | 27.7 | 19 | 38.0 | 50 | 35.2 | 28 | 39.4 | 535 | 28.3 |
| 0.6 – 0.9 mm | 270 | 16.7 | 5 | 10.0 | 37 | 26.1 | 14 | 19.7 | 316 | 16.7 |
| ≥ 1 mm | 236 | 14.6 | 7 | 14.0 | 9 | 6.3 | 20 | 28.2 | 284 | 15.0 |
| Unknown | 138 | 8.5 | 3 | 6.0 | 3 | 2.1 | 2 | 2.8 | 155 | 8.1 |
| Clark level of CMM* | ||||||||||
| 1 | 392 | 24.2 | 13 | 26.0 | 35 | 24.7 | 0 | 0.0 | 448 | 23.7 |
| 2 | 622 | 38.4 | 28 | 56.0 | 74 | 52.1 | 11 | 15.5 | 695 | 36.7 |
| 3 | 265 | 16.4 | 4 | 8.0 | 23 | 16.2 | 14 | 19.7 | 301 | 15.9 |
| 4 | 140 | 8.6 | 1 | 2.0 | 4 | 2.8 | 1 | 1.4 | 144 | 7.6 |
| 5 | 11 | 0.7 | 0 | 0.0 | 0 | 0.0 | 1 | 1.4 | 13 | 0.7 |
| Unknown | 189 | 11.7 | 4 | 8.0 | 6 | 4.2 | 44 | 62.0 | 293 | 15.4 |
*
CMM, Cutaneous Malignant Melanoma; QFMP, Queensland Familial Melanoma Project; Q-MEGA, Queensland study of Melanoma: Environmental and Genetics Associations.
†
20 subjects were both included in the QFMP and in the children study, and 82 subjects participated both in the QFMP and the adolescents study.