Table 1. Structure-activity relationship data for lithocholic acid derivatives.

Cpd.	R1	R2	R3	R4	R5	Ki (μM)[a]
1						49±3.0
2						>200
3						>200
4						>200
5						114±13
6						138±20
7						157±47
8						114±14
9						88±11
10						25±4.0
11						>200
12						5.1±1.4
13						>200
14						>200
15						>200
16						186±27

^[a]Values are means ± standard error from at least three independent experiments