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. 2013 Feb 20;33(6):888–897. doi: 10.1038/jcbfm.2013.26

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Copyright © 2013 International Society for Cerebral Blood Flow & Metabolism, Inc.

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Voxel analysis: LEGA RR, MRTMo, and MRTM. Scatter plots of BP_ND,IF (X-axis; region of interest (ROI) analysis) and BP_ND,im (Y-axis; average within each target region) for 10 randomly selected subjects for [¹¹C]CUMI (left panel), [¹¹C]BTA, [¹¹C]ABP, and [¹¹C]DASB (right panel). The X-axis is the full cIF (ROI) analysis (LEGA for [¹¹C]DASB and [¹¹C]CUMI; Logan for [¹¹C]BTA); 2TC for [¹¹C]ABP). BP_ND, nondisplaceable binding potential; cIF, metabolite-corrected IF; IF, input function; LEGA, likelihood estimation in graphical analysis; MRTM, multilinear reference tissue model; RR, reference region; 2TC, two-tissue compartment.