Skip to main content
. Author manuscript; available in PMC: 2014 May 9.
Published in final edited form as: Cell. 2013 May 9;153(4):828–839. doi: 10.1016/j.cell.2013.04.015

Figure 4. Differences in blood pressure between young CD45.1 and CD45.2 mice do not explain the reversal of cardiac hypertrophy.

Figure 4

(A) Graph representing the heart weight / tibia length ratio after 4 weeks of parabiosis, using only CD45.2 mice.

(B) Left ventricular myocyte cross-sectional area based on PAS staining in CD45.2 mice. Exposure of an old mouse to the circulation of a young CD45.2 mouse reverses cardiac hypertrophy.

(C) Old mice conjoined to young CD45.1 or CD45.2 mice show no difference in blood pressure measured by the tail-cuff system (Fig. 3A) after 4 weeks.

(D) No significant intergroup differences in blood pressure were detected with terminal intra-arterial catheter-based measurements. Data shown as mean ± s.e.m.