Table 2.
Studies evaluating treatment of neglect by tDCS.
Study | No. of patients | Time post | Sham control | Stimulation site (contra/ipsilesional) | Protocol | No. of sessions | Time of assessment in relation to stimulation | Outcome measures | Main results | Descriptive magnitude of the changes in the main outcome measures |
---|---|---|---|---|---|---|---|---|---|---|
Ko et al. (2008) | 15 RH | 29–99 d | Yes | Ipsi P4 | 2.0 mA anodal stimulation for 20 min | 1 session | Pre/post | Line bisection test, letter-structured cancelation test, shape-unstructured cancelation test | Sign. effects of real tDCS on line bisection test and shape-unstructured cancelation test | On average: −3.52 percent deviation score in the line bisection test (= ∼ −19%); −3.47 omissions in the shape-unstructured cancelation test (= ∼ −14.8%) |
Sparing et al. (2009) | 10 RH | 0.5–12.4 m | Yes | Contra P3 and ipsi P4 | 1.0 mA anodal and cathodal stimulation for 10 min | 2 sessions, cross-over | Pre/post | Line bisection test, visual detection task | Sign. improvement in line bisection test after anodal tDCS of the lesioned hemisphere and cathodal tDCS of the intact hemisphere | On average: in the line bisection test, from 3.4 mm deviation pre (rightwards bias) to -1.5 mm post (leftward bias) with anodal tDCS on P4; from 5.4 mm pre to −1.7 mm post with cathodal tDCS on P3 |
w, week; m, month; d, day; MT motor threshold; MMSE, Mini Mental State Examination; BRS, Brunnstrom Recovery Index; BI, Barthel Index; PVT, subtest of the Vienna Test System (detection of peripheral visual targets); CBS, Catherine Bergego Scale; MEP, motor-evoked potential; RH, right hemisphere; LH, left hemisphere; RT, reaction time; K-MBI, Korean-Modified Barthel Index; SEM, standard error of the mean; pts, points.
*These values have been visually inferred from the graphs provided in the respective studies.