Table 1.

Baseline predictors of more severe patient- vs clinician-rated depression severity during acute and continuation treatment.

	Odds Ratio (95% CI)
	Age	Body mass index	Male vs female	Lifetime MDD episodes
Acute Phase
Baseline	0.96 (0.94–0.98) ‡	1.09 (1.05–1.13)§	0.54 (0.32–0.90)*	1.01 (1.00–1.02)*
Week 1	0.97 (0.95–0.99)†	1.06 (1.02–1.10)†	0.45 (0.27–0.76)†	1.00 (0.99–1.01)
Week 2	0.98 (0.96–1.00)	1.05 (1.02–1.09)†	0.47 (0.28–0.79)†	1.01 (1.00–1.02)*
Week 3	1.00 (0.98–1.02)	1.05 (1.01–1.09)†	0.76 (0.44–1.29)	1.00 (0.99–1.01)
Week 4	1.00 (0.98–1.03)	1.07 (1.03–1.11)‡	0.42 (0.24–0.74)†	1.00 (1.00–1.01)
Week 6	1.01 (0.99–1.03)	1.06 (1.02–1.10)†	0.46 (0.25–0.82)†	1.00 (0.99–1.01)
Week 8	1.02 (1.00–1.04)	1.03 (0.99–1.07)	0.67 (0.38–1.17)	1.00 (0.99–1.01)
Week 10	1.02 (1.00–1.05)	1.02 (0.98–1.06)	0.53 (0.29–0.98)*	1.00 (0.99–1.01)
Continuation Phase
Month 1	1.03 (1.00–1.06)*	1.02 (0.98–1.07)	0.59 (0.29–1.20)	1.01 (1.00–1.02)
Month 2	1.02 (0.99–1.04)	0.99 (0.95–1.04)	0.67 (0.33–1.38)	1.01 (1.00–1.02)
Month 3	1.03 (1.00–1.06)	1.00 (0.95–1.05)	1.52 (0.71–3.29)	1.01 (0.99–1.02)
Month 4	1.02 (0.99–1.06)	1.02 (0.97–1.08)	1.16 (0.53–2.52)	1.01 (0.99–1.02)
Month 5	1.04 (1.00–1.07)*	1.00 (0.95–1.05)	0.98 (0.43–2.26)	1.00 (0.98–1.01)
Month 6	1.06 (1.02–1.09)‡	1.02 (0.97–1.08)	0.99 (0.43–2.28)	1.01 (0.99–1.02)

CI = confidence interval; MDD = major depressive disorder.

^*P<0.05;

^†P≤ 0.01;

^‡P< 0.001;

^§P< 0.0001.