Figure 2. Anatomic deformation.
Two example vessel bifurcations, which were selected as reference landmark features, are shown in transverse section with green crosshair indicating corresponding voxel positions in (a, c) iBH- and (b, d) eBH-CT. There is substantial change in the shape of the structures that make-up the bifurcations. On the iBH-CT the blood vessels are straight and the lung tissue is dark. On the eBH-CT the blood vessels are bent, due to the substantially reduced lung volume, and the surrounding lung tissue is lighter. The bifurcations shown are located much closer to the lung border on the eBH-CT. These changes make automated estimation of these point-pairs difficult using cross-correlation.