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. Author manuscript; available in PMC: 2013 Jun 10.
Published in final edited form as: Science. 2013 Mar 1;339(6123):1222002. doi: 10.1126/science.1222002

Figure 2.

Figure 2

A. Still frames from a time lapse movie showing neural tube closure in an amphibian embryo (rostral = up). B. Disruption of PCP signaling results in disrupted neural tube closure (red bracket). C. Still frame from a movie of mouse neural tube closure; arrows indicate initial meeting of neural folds (47). c′. Neural tube closure has progressed in a later time point. D. Genetically-inducible fluorescent reporters allow visualization of specific tissues (green), in this case the ectoderm that borders the neural tissue.