Fig. 5.

DNA repair process after radiation at 1 Gy. a The number of γH2AX foci increases in a dose-dependent manner. The LECs from C57BL/6J mice show more foci than the other cells. Data are presented as mean ± SEM (n between 2 and 5; except for the JF1 LEC data at the doses of 0.25 Gy and 0.5 Gy with n = 1). b The number of γH2AX foci after irradiation at 1 Gy and incubation time of 1 h was set to 1 (i.e., relative spot counts are shown); it decreases with increasing incubation time, which was allowed for 24 h. Repair proceeds faster in the LECs compared to lymphocytes; the strain effect on repair is different between the cell types (p value for interaction effect in the three-way ANOVA; p = 0.0096). Data are presented as mean ± SEM (n between 2 and 5; except for the JF1 LEC data at the incubation time of 4 h and the C57BL/6 lymphocyte data at the incubation time of 24 h with n = 1)