Skip to main content
. 2013 Apr;19(4):510–516. doi: 10.1261/rna.036038.112

FIGURE 2.

FIGURE 2.

Decoding of tRNAAlaGGC mutations on cognate and near-cognate codons. (A) Time course of conversion of [3′-P32] Ala-tRNAAla to fMet-Ala-tRNAAla for unmodified wild type (black), G31-C39 mutation (green), and U31-A39 mutation (red) using the cognate GCC codon (left) or near-cognate ACC codon (right). (B) Fraction of fMet-Ala-tRNAAla formed at completion (10 sec) for native and unmodified tRNAAla (black), six consensus mutations (green), and 16 nonconsensus mutations (red) using GCC, GUC, and ACC codons. Horizontal blue bars indicate range of values observed for wild-type tRNA.