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. 2013 Apr;19(4):552–560. doi: 10.1261/rna.035972.112

FIGURE 5.

FIGURE 5.

MiR-181b overexpression suppressed tumor angiogenesis in vivo. (A) Representative Matrigel plugs are shown. Scale bar, 2 mm. (B) The hemoglobin levels in eight tumors from the miR-181b group were decreased 50% compared with the miR-NC group. (**) Significant difference when compared with the miR-NC group (P < 0.01). (C) Representative tumor sections stained with antibody against human CD31. Magnification, 200×. (D) CD31-positive microvessels were counted from eight tumors in three different fields per section at 400× magnification. (**) Significant difference compared with the miR-NC group (P < 0.01).