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. 2013 Apr 23;21(6):1251–1258. doi: 10.1038/mt.2013.53

Figure 2.

Figure 2

CCSP+ BMC express epithelial and ion channel proteins in the host lung. Confocal microscopic analysis of Clara cell marker (a–d) CCSP, (e–h) CFTR, and (i–l) ENaC. Donor cells were identified by CMTMR positive fluorescence (red). The first and second columns show merged images with donor double-positive cells; the third column shows donor cells (red), whereas the fourth column shows single color imaging for each protein analyzed. Insets are representative isotype staining controls. Arrows point to donor double-positive cells and arrowheads indicate host single-positive cells. Scale bar represents 10 µm. n = 4 mice per group. Samples from mice administered with donor cells after 10 days of ganciclovir. BMC, bone marrow cells; CCSP, Clara cell secretory protein.