Mice treated with CCSP+
BMC have less inflammatory cells in bronchoalveolar lavage fluid. To avoid analyzing samples of moribund mice from the CCSP− BMC group, lungs from mice treated with cells after only 5 days of ganciclovir treatment were analyzed. (a) Bronchoalveolar lavage (BAL) from mice treated with CCSP− BMC had 1.79 ± 0.34 million cells in the total cell count, whereas the CCSP+ BMC group had 0.59 ± 0.10 million (*P = 0.015). (b) The differential cell count analysis of BAL cells shown significantly less neutrophils (3.53 ± 0.0002%) and more macrophages (76.6 ± 0.01%) in the CCSP+ BMC group compared with the CCSP− BMC group (neutrophils, 25.8 ± 1.6% and macrophages, 35.6 ± 1.4%; *P < 0.01). Data shown are means ± SEM. n = 8 mice per group. BMC, bone marrow cells; CCSP, Clara cell secretory protein; Eos, eosin; Mac, macrophages; Lym, lymphocytes; Neu, neutrophils.