Table 2.
Molecular form and kdr status | % (N) | Sporozoite rate | |
% Pf (n) | Odds ratio [95% CI] | ||
Total A. gambiae | 100 (4,500) | 2.6 (119) | |
Kdr* | |||
Homozygous susceptible (SS), % | 45 (1,741) | 2.4 (42) | 1 |
Heterozygous (SRw), % | 41 (1,564) | 4.4 (69) | 1.9 [0.91–3.8], P = 0.090 |
Homozygous resistant (RwRw), % | 14 (543) | 1.1 (6) | 0.45 [0.25–0.83], P = 0.01 |
Molecular form | |||
M form, % | 36 (1,495) | 2.1 (31) | 1 |
S form, % | 64 (2,700) | 3.3 (88) | 1.6[0.98–2.6], P = 0.061 |
Seven specimens were heterozygous for the east African variant of kdr SRe, and 5 were ReRw (all sporozoite negative). For 640 specimens, no kdr status was available (all SEs adjusted for between cluster differences).