Table 2.
Adjusted bivariate and block-stepwise multivariable logistic regression models examining associations of demographics, HIV disease stage and treatment, sexual risk, and mental health indicators with stimulant and depressant class drugs
| Drug class: stimulants |
Drug class: depressants |
|||
|---|---|---|---|---|
| Adjusted bivariatea | Final multivariable | Adjusted bivariate | Final multivariable | |
| Demographics | ||||
| Age | 0.97 (0.95, 0.99)* | 0.98 (0.94, 1.01) | ||
| Education | ||||
| <College degree | 1.00 | 1.00 | ||
| College degree | 0.94 (0.60, 1.49) | 0.80 (0.43,1.49) | ||
| Graduate degree | 0.91 (0.51, 1.63) | 0.79 (0.37, 1.68) | ||
| Income | ||||
| ≤$40,000 | 1.00 | 1.00 | ||
| $40,001–$80,000 | 0.78 (0.49, 1.26) | 1.21 (0.64, 2.29) | ||
| >$80,000 | 0.86 (0.47, 1.60) | 1.16 (0.51, 2.61) | ||
| Race/ethnicity | ||||
| White | 1.00 | 1.00 | 1.00 | |
| Black | 1.39 (0.74, 2.62) | 0.24 (0.07, 0.85)* | 0.23 (0.06, 0.85)* | |
| Hispanic | 0.84 (0.39, 1.79) | 0.39 (0.11, 1.42) | 0.37 (0.09, 1.46) | |
| Other | 1.67 (0.45, 3.00) | 0.43 (0.11, 1.70) | 0.47 (0.12, 1.87) | |
| Primary partner | ||||
| No | 1.00 | 1.00 | ||
| Yes | 0.91 (0.60, 1.40) | 1.01 (0.58, 1.78) | ||
| HIV disease stage and treatment | ||||
| Plasma RNAb | ||||
| ≤75 copies/ml | 1.00 | 1.00 | 1.00 | 1.00 |
| >75 copies/ml | 1.98 (1.31, 3.00)** | 1.70 (1.08, 2.69)* | 1.85 (1.07, 3.19)* | 2.20 (1.21, 4.00)* |
| Currently on HIV medication | ||||
| No | 1.00 | 1.00 | ||
| Yes | 0.65 (0.42, 1.01)* | 1.02 (0.57, 1.82) | ||
| Sexual risk | ||||
| Transmission risk behavior | ||||
| No | 1.00 | 1.00 | 1.00 | |
| Yes | 2.59 (1.69, 3.98)*** | 2.54 (1.63, 3.94)*** | 1.73 (0.97, 3.08)~ | |
| Sexually transmitted infections | ||||
| No | 1.00 | 1.00 | ||
| Yes | 1.53 (0.67, 3.48) | 1.15 (0.41, 3.21) | ||
| Mental health | ||||
| Depression | ||||
| No depression | 1.00 | 1.00 | 1.00 | |
| Other depressive disorder | 1.38 (0.70, 2.75) | 1.40 (0.69, 2.84) | 1.04 (0.40, 2.71) | |
| Major depressive disorder | 2.25 (1.23, 4.10)** | 2.09 (1.12, 3.90)* | 2.08 (1.03, 4.23)* | |
| Anxiety disorder | ||||
| No | 1.00 | 1.00 | ||
| Yes | 1.62 (1.06, 2.48)* | 1.80 (1.00, 3.24)~ | ||
| ADHD | ||||
| No | 1.00 | 1.00 | 1.00 | |
| Yes | 1.37 (0.69, 2.75) | 2.17 (1.03, 4.58)* | 2.28 (1.08, 4.79)* | |
| Childhood sexual abuse | ||||
| No | 1.00 | 1.00 | ||
| Yes | 1.28 (0.84, 1.94) | 1.30 (0.75, 2.23) | ||
~
p<0.10;
*
p<0.05;
**
p<0.01;
***
p<0.001
a
All bivariate and multivariable models adjusted for a multiple drug use variable that did not include the drugs in the outcome class
b
CD4 count was added as a covariate when viral load was included in multivariable models