Figure 5. Expression of key determinants of mitochondrial biogenesis and mitochondrial proteins.
A) Real-time PCR measurement of transcript levels of mitochondrial protein NRF-1, TFAM, and COX in samples from CONT and HFLCD hearts. B) Western blot analyses of levels of NRF1 and TFAM in samples of CONT and HFLCD hearts. C) Relative Mitochondrial DNA copy number in samples from CONT and HFLCD hearts. Values are expressed as means±SEM, n=5–6 each, * P < 0.05 compared with CONT.