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. Author manuscript; available in PMC: 2013 Jul 10.
Published in final edited form as: N Engl J Med. 2012 Nov 14;368(2):107–116. doi: 10.1056/NEJMoa1211103

Table 1.

Association between the rs75932628-T Variant and Alzheimer’s Disease in Comparisons with Three Control Groups.

Control Group No. of Participants Frequency Odds Ratio (95% CI) P Value
%
All population controls 110,050 0.63 2.26 (1.71–2.98) 1.13×10−8
Population controls ≥85 yr of age 8,888 0.46 2.92 (2.09–4.09) 3.42×10−10
Cognitively intact controls ≥85 yr of age* 1,236 0.31 4.66 (2.38–9.14) 7.39×10−6
*

Intact cognition was defined as a score of 0 on the Cognitive Performance Scale, which ranges from 0 to 6, with higher scores indicating more severe impairment. CI denotes confidence interval.