Table 2.
Comparative analysis between patients with and without thyroid nodules in Graves' disease and Hashimoto's thyroiditis.
| Graves' disease (n = 198) | Hashimoto's thyroiditis (n = 77) | |||||
|---|---|---|---|---|---|---|
| With nodules | Without nodules | P | With nodules | Without nodules | P | |
| Gender—male/female (%) | 4/51 (2.02/25.76) | 14/129 (7.07/65.15) | 0.581 | 2/37 (2.6/48.05) | 3/35 (3.9/45.45) | 0.675 |
| Age—yrs (range) | 53 (27–84) | 43 (13–82.8) | <0.001 | 55 (15–84) | 49.5 (17–79) | 0.421 |
| Age at diagnosis—yrs (range) | 46 (17–81) | 36 (9–77) | <0.001 | 47 (5–70) | 43.5 (14–77) | 0.194 |
| Disease duration—yrs (range) | 6 (0.6–20) | 5.0 (0.5–27) | 0.074 | 7 (0.2–16) | 7 (0.1–21) | 0.953 |
| Total thyroid volume—cc (range) | 29.8 (4.1–242) | 23.1 (1.6–201.3) | 0.019 | 18.5 (1–111.9) | 9.8 (2.1–69.2) | 0.005 |
| Time of followup—yrs (range) | 6 (0.3–20) | 5 (0.1–20) | 0.077 | 7 (0.2–16) | 7 (0.1–21) | 0.779 |
| Smoking (%)a | 18 (13.53) | 49 (36.84) | 0.885 | 9 (26.47) | 5 (14.71) | 1.0 |
| Time of treatment—yrs (range) | 4 (0.3–17) | 3 (0.1–20) | 0.433 | 6 (1–16) | 7 (1–15) | 0.945 |
| Ophthalmopathy (%)b | 22 (16.06) | 70 (51.09) | 0.077 | NA | NA | NA |
| Active disease (%) | 50 (25.25) | 126 (63.64) | 0.575 | NA | NA | NA |
| Radioiodine treatment (%) | 17 (8.59) | 49 (24.75) | 0.654 | NA | NA | NA |
| 99mTc uptake—% (range) | 7 (0.2–82) | 10 (0.3–77) | 0.138 | NA | NA | NA |
a n = 133 for GD and n = 34 for HT.
b n = 137 for GD.
NA: not available.