Table 1.
Treatment | FBG (mmol/L) | ||||
---|---|---|---|---|---|
Day 0 | Day 7 | Day 14 | Day 21 | Day 28 | |
Diabetic control | 11.88 ± 0.49 | 13.73 ± 0.56 | 15.53 ± 0.34 | 15.39 ± 0.35 | 15.40 ± 0.65 |
Rosiglitazone | 11.33 ± 0.29 | 8.82 ± 0.86** | 8.08 ± 0.54** | 7.48 ± 0.37** | 7.23 ± 0.28** |
Normal control | 5.09 ± 0.12** | 5.47 ± 0.96** | 5.38 ± 0.82** | 5.43 ± 0.85** | 5.30 ± 0.55** |
TLSP 200 mg/kg | 11.57 ± 0.46 | 8.54 ± 0.26** | 7.70 ± 0.45** | 7.03 ± 0.41** | 6.84 ± 0.37** |
TLSP 100 mg/kg | 11.56 ± 0.36 | 8.82 ± 0.61** | 7.50 ± 0.50** | 7.05 ± 0.46** | 6.86 ± 0.68** |
LSP1 200 mg/kg | 11.69 ± 0.47 | 8.68 ± 0.45** | 7.59 ± 0.27** | 7.13 ± 0.53** | 7.09 ± 0.25** |
LSP1 100 mg/kg | 12.1 ± 0.32 | 9.03 ± 0.52** | 7.46 ± 0.30** | 7.10 ± 0.43** | 7.30 ± 0.59** |
LSP2 200 mg/kg | 12.17 ± 0.54 | 8.86 ± 0.48** | 7.71 ± 0.33** | 7.31 ± 0.23** | 7.13 ± 0.40** |
LSP2 100 mg/kg | 12.67 ± 0.71 | 9.02 ± 0.60** | 7.59 ± 0.24** | 7.15 ± 0.30** | 7.15 ± 0.29** |
Data were presented as mean ± SD (n = 7-8). **P < 0.01 versus diabetic control (vehicle-treated).