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. 2013 May 15;9(5):472–479. doi: 10.7150/ijbs.5855

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Cell invasion assay of CD133⁺/CD44⁺DU145 cells. CD133⁺/CD44⁺ cells isolated from DU145 cultures have increased migratory and invasive capacities. (A) Parental DU145 cells, (B) CD133⁺/CD44⁺ cells, (C) CD133⁺ /CD44⁺ cells showing a 4-fold increase in the number of cells migrating through a Matrigel-coated membrane compared to parental cells (CD133⁺/CD44⁺ cells versus the parental cells, 416 ± 47 versus 109 ± 24, * p < 0.001).