Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 May 15;9(5):472–479. doi: 10.7150/ijbs.5855

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

PMC Copyright notice

(A) Growths in BALB/c nude mice after inoculation with CD133⁺/CD44⁺ cells taken from DU145 cultures. (B) Xenograft tumor growth curve for week 1 to 8 for all mice. At 8 weeks, xenograft tumor volume in CD133⁺/CD44⁺ DU145 cells was bigger than that of parental DU145 cells (CD133⁺/CD44⁺ cells versus the parental cells, 813.26 ± 122.66 mm³ versus 443.87 ± 73.17 mm³, * p < 0.001). (C) Histological analysis of subcutaneous tumors using hematoxylin and eosin staining shows cancer cell-specific features (irregularly packed tumor cells, hyperchromatic nuclei, prominent nucleoli and many mitotic cells). (D) Immunofluorescence double-staining visualized by confocal microscopy. CD133 is shown in red and CD44 in green.