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. Author manuscript; available in PMC: 2013 Jun 10.
Published in final edited form as: Exp Hematol. 2007 Jan;35(1):21–31. doi: 10.1016/j.exphem.2006.08.017

Figure 1.

Figure 1

Culture in 3% O2 enhances colony-forming unit (CFU) yield from myelodysplastic syndrome (MDS) mononuclear cells (MNCs). Myeloid (A) and erythroid (B) CFUs from MNCs of normal volunteer donors (“Normal” on far right) and MDS patients (indicated by unique sample numbers) were counted following 14 days of culture in either standard conditions using 18.6% O2 (white bars) or in 3% O2 (gray bars). Results are normalized to CFUs per 104 MNCs. Broken bars represent samples with > 150 colonies per 1-mL plate. Samples 234 and 253 were collected from the same patient, R0306, prior to and following 6 weeks of treatment with the histone deacetylase inhibitor valproic acid.