Table 1. Antagonists binding at the GluN1 subunit.

	R	[3H]-MDL-105,519 binding IC50 [μM]	Patch-clamp IC50 [μM]	Calcium FLIPR IC50 [μM]
34		0.0119	0.023	0.211
42		0.055	0.050	0.105
59		0.083	0.059	0.88