Figure 5.
Sequence logos derived from alignment of the primary sequences of the four TM segments of the Karlodinium proton channel, kHV1 (top row) with the TM segments of 37 members of the HV1 family, 15 of C15orf27, 15 of VSP, and 13 KV channels. The letter height (single letter amino acid abbreviations) in the sequence logos shows the proportion of all sequences with a particular amino acid at that position. The overall height of the stack indicates information content (439) or sequence conservation at that position (88). The mean (± SD) numbers of amino acids in the N and C termini are given to the left and right, respectively. The examples numbered for each family are hHV1, human C15orf27, CiVSP, and Shaker for KV. [From Smith et al. (462).]