Table 3.
Characteristics of cases of TEC and drug exanthem
| Palmar-plantar erythema (n = 2) | TEC (n = 4) | Drug exanthem (n = 9) | TEC vs drug exanthem (n = 4) | |
|---|---|---|---|---|
| Mean age in years | 31.0 (range 19–43) |
47.5 (range 35–59) |
62.6 (range 46–85) |
56.3 (range 52–62) |
| Male:female ratio | 1:1 | 3:1 | 6:3 | 1:3 |
| Mean duration between chemotherapy and onset of rash | 29* | 9.5 days (range 3–23) |
16.8 days (range 4–24)** |
11.5 days (range 2–20) |
| Presence of neutropenia at time of rash | 1/2 | 3/4 | 6/8*** | 3/4 |
| Intensity of itch | ||||
| None | 2 | 2 | 1 | 2 |
| Mild | – | 2 | 2 | 2 |
| Moderate | – | – | – | – |
| Severe | – | – | 2 | – |
| Unspecified | – | – | 4 | – |
| Mean number of drugs at onset of rash | NA | 8 (range 6–10) |
6.7 (range 3–15) |
8.5 (range 5–15) |
Notes:
*
Data available only from 1 patient;
**
data available only for 6 patients;
***
data available only for 8 patients.
Abbreviations: NA, not available; TEC, toxic erythema of chemotherapy.