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Superposition of the binding modes of three peroxisome proliferator–activated receptor γ (PPARγ) synthetic ligands. Rosiglitazone is a full agonist, BVT.13 is a partial agonist, and GW9662 is a suicide inhibitor that binds to the receptor pocket. Together, the superposition shows the Y-shaped inducible fit possible in this receptor pocket (157).
