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Nuclear receptor interactions with lipid molecules. LRH-1 is shown with phosphotidyl glycerol, SF-1 with di-palmitoyl-3-SN-phosphotidylethanolamine, HNF4-α with myristic acid, and peroxisome proliferator–activated receptor γ (PPARγ) with 9-HODE (7, 8). LRH-1, liver receptor homolog-1; HNF-4, hepatocyte nuclear factor-4; SF-1, steroidogenic factor-1.
