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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Behav Brain Res. 2013 Mar 26;248:12–24. doi: 10.1016/j.bbr.2013.03.028

Figure 2. Repeated restraint led to reduced open arm exploration of EPM.

Figure 2

(A) Repeated restraint resulted in reduced time spent on open arm of EPM in both adolescent (right) and adult (left) rats, indicating increased anxiety state after repeated restraint. (B) There was no significant difference in the total number of arm entries in both adolescent (right) and adult (left) rats, indicating no changes in locomotor activity. Black represents non-restraint controls, white represents restraint groups. ***p < 0.001 compared between non-restraint and repeated restraint groups.