Table 2. Characteristics of the patients treated with SC-treprostinil.
Patient | Sex | Cause of PAH | Age at diagnosis of PAH | Age at initiation of first treatment | Age at initiation of dual therapy | Age at initiation of SC treprostinil over both oral therapy | Oxygen saturation | NYHA functionnal class |
1 | M | Postoperative, TGA | 3 months | 7 months, bosentan | 19 months, sildenafil | 4 years | 95% | III |
2 | M | Postoperative PDA | 3.5 years | 3.5 years, sildenafil | 4 years, bosentan | 5.5 years | 86% | III |
3 | F | Small defect, VSD | 2 months | 9 months, sildenafil | 10 months, bosentan | 2.5 years | 98% | III |
4† | F | Small defect, ASD | 6 years | 7 years, bosentan | 7 years, sildenafil | 10 years | 71% | IV |
5 | M | iPAH (Heritable) | 4 months | 5 months, sildenafil | 6 months, bosentan | 15 months | 95% | III |
6† | M | iPAH | 3 months | 4.5 years, bosentan | 6.5 years sildenafil | 10 years | 89% | IV |
7 | F | iPAH | 2 years | 2 years, IV epoprostenol | 5 years bosentan 7 years, sildenafil | 9 years | 98% | II |
8 | M | iPAH | 16 months | 16 months, bosentan | 22 month, sildenafil | 2.5 years | 88% | IV |
9 | F | iPAH | 12 years | 12 years, directly tritherapy | / | 12 years | 94% | IV |
10 | F | iPAH | 4 years | 4 years | 4 years sildenafil and bosentan | 5 years | 98% | IV |
TGA, transposition of the great arteries; PDA, patent ductus arteriosus; VSD, ventricular septal defect; ASD, atrial septal defect.
Deceased.