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. 2013 Jun 10;8(6):e65114. doi: 10.1371/journal.pone.0065114

Table 2. Characteristics of the patients treated with SC-treprostinil.

Patient Sex Cause of PAH Age at diagnosis of PAH Age at initiation of first treatment Age at initiation of dual therapy Age at initiation of SC treprostinil over both oral therapy Oxygen saturation NYHA functionnal class
1 M Postoperative, TGA 3 months 7 months, bosentan 19 months, sildenafil 4 years 95% III
2 M Postoperative PDA 3.5 years 3.5 years, sildenafil 4 years, bosentan 5.5 years 86% III
3 F Small defect, VSD 2 months 9 months, sildenafil 10 months, bosentan 2.5 years 98% III
4 F Small defect, ASD 6 years 7 years, bosentan 7 years, sildenafil 10 years 71% IV
5 M iPAH (Heritable) 4 months 5 months, sildenafil 6 months, bosentan 15 months 95% III
6 M iPAH 3 months 4.5 years, bosentan 6.5 years sildenafil 10 years 89% IV
7 F iPAH 2 years 2 years, IV epoprostenol 5 years bosentan 7 years, sildenafil 9 years 98% II
8 M iPAH 16 months 16 months, bosentan 22 month, sildenafil 2.5 years 88% IV
9 F iPAH 12 years 12 years, directly tritherapy / 12 years 94% IV
10 F iPAH 4 years 4 years 4 years sildenafil and bosentan 5 years 98% IV

TGA, transposition of the great arteries; PDA, patent ductus arteriosus; VSD, ventricular septal defect; ASD, atrial septal defect.

Deceased.