Table 3. Effect of SC treprostinil therapy on functional and hemodynamic status.
Patient N° | 1 | 2 | 3 | 4† | 5 | 6† | 7 | 8 | 9 | 10 | ||||||||||
Follow-up (months) | 24 | 18 | 20 | 2 | 21 | 6 | 36 | 6 | 12 | 12 | ||||||||||
before | after | before | after | before | after | before | after | before | after | before | after | before | after | before | after | before | after | before | after | |
SaO2 | 92 | 100 | 86 | 97 | 90 | 98 | 70 | 75 | 100 | 100 | 98 | 98 | 99 | 99 | 88 | 97 | 94 | 98 | 98 | 98 |
NYHA | III | I | III | II | III | II | IV | IV | III | II | IV | III | II | II | IV | II | IV | I | IV | II |
6MWT(m) | 110 | 360 | 140 | 360 | 200 | 420 | 240 | 250 | – | – | – | – | 400 | 520 | – | – | 100 | 570 | 200 | 470 |
BNP pg/mL | 27 | 35 | 8 | 5 | 39 | 14 | 1220 | 837 | 47 | 8 | 283 | 1150 | 28 | 28 | 480 | 400 | 382 | 5 | 6 | 5 |
PAP mean(mmHg) | 63 | 71 | 60 | 63 | 40 | 60 | 60 | – | 83 | 103 | 65 | – | 60 | 55 | 60 | 60 | 68 | 68 | 72 | 70 |
SAP mean(mmHg) | 73 | 83 | 56 | 64 | 63 | 63 | 58 | – | 85 | 80 | 60 | – | 75 | 91 | 55 | 55 | 85 | 87 | 85 | 70 |
CO(L/min) | 2,6 | 3,6 | 4,7 | 4,8 | 2,6 | 2,3 | 3,7 | – | 2,2 | 3,3 | 2,2 | – | 3,6 | 4 | – | – | 2,3 | 5,2 | 3 | 2,1 |
PVR(Woods Units) | 20,4 | 15,8 | 11,5 | 11 | 21,4 | 23 | 19 | – | 35,5 | 28,8 | 24,8 | – | 14,8 | 11,5 | 19,9 | – | 25 | 12 | 21 | 7 |
Deceased.