Table 4. Serum markers of renal, hepatic, and endocrine function and injury.
| Serum analyte | MoMHR (n = 35) | THA (n = 35) |
| Renal function and injury | ||
| Sodium (mmol/L) | 144.5±2.7 | 144.3±2.8 |
| Potassium (mmol/L) | 4.5 ±0.4 | 4.5±0.3 |
| Urea (mmol/L) | 5.6±1.9 | 5.1±1.1 |
| Creatinine (mmol/L) | 91.2±20.0 | 88.6±18.3 |
| Creatinine clearance (mL/min/1.73 m2) | 111.6±35.3 | 99.1±28.0 |
| ‡Kidney injury molecule-1 (ng/mL) | 0.7±0.5 | 0.8±0.1 |
| ‡N-acetyl-β-(D)-glucosamidase (ng/mL) | 25.2±13.4 | 26.3±16.7 |
| ‡Neutrophil gelatinase-associated lipocalin (ng/mL) | 2.9 (1.8 to 4.7) | 2.9 (1.8 to 3.8) |
| Hepatic function and injury | ||
| Total protein (g/L) | 71.7±3.8 | 73.5±4.8 |
| Albumin (g/L) | 44.6±2.3 | 45.1±3.3 |
| Globulin (g/L) | 27.1±3.7 | 28.4±3.0 |
| Serum ferritin (µg/L) | 174.1±134.0 | 193.1±137.4 |
| Serum transferrin receptor | 2.6±0.4 | 2.6±0.4 |
| Adjusted calcium (mmol/L) | 2.3±0.1 | 2.4±0.1 |
| Total bilirubin (µmol/L) | 13.4 ±7.8 | 12.4±6.1 |
| Alkaline phosphatase (IU/L) | 61.7±15.3 | 63.3±15.6 |
| Alanine transaminase (IU/L) | 31.7±9.6 | 29.7±10.4 |
| Prothrombin time (seconds) | 10.6±0.7 | 10.6±0.4 |
| Activated partial thromboplastin time (seconds) | 30.9±3.0 | 31.7±3.7 |
| Fibrinogen (g/L) | 3.3±0.8 | 3.4±0.7 |
| Endocrine function | ||
| Thyroid stimulating hormone (mIU/L) | 2.3 ±1.4 | 2.2±1.2 |
| Free tri-iodothyronine (pmol/L) | 5.4±0.6 | 5.4±0.6 |
| Luteinising hormione (IU/L) | 4.8 (3.5 to 12.4) | 4.8 (3.5 to 8.8) |
| Follicle stimulating hormone (IU/L) | 6.1 (4.6 to 21.8) | 6.4 (4.4 to 12.4) |
| Prolactin (mIU/L) | 145.5±64.3 | 153.2±93.0 |
| Cortisol (nmol/L) | 423.7±136.7 | 397.9±107.7 |
| ‡Testosterone (nmol/L) | 15.3±6.3 | 14.2±5.7 |
| Oestradiol (mIU/L) | 35.4±9.5 | 31.5±12.9 |
| Growth hormone (µg/L) | 0.4 (0.1 to 0.8) | 0.40 (0.1 to 1.0) |
| Fasting insulin (mIU/L) | 11.1±6.3 | 10.2±6.0 |
| Fasting glucose (mmol/L) | 6.2±1.0 | 5.9±1.1 |
| Fasting glucose to insulin ratio (mmol/mIU) | 0.8±0.5 | 0.9±0.9 |
Values are mean ± standard deviation or median (interquartile range). Analysis is MoMHR versus THA by paired-t test or Wilcoxon test. P>0.05 all comparisons. ‡Marker assayed in men only (n = 31 per group).