Table 5. Genetic polymorphism of HA_H5 genes in the globular head region.

	Amino acid residue in HA ofb
Amino acid positiona (antigenic site)	A/chicken/Yamaguchi/7/2004 (H5N1) clade 2.5	A/whooper swan/Mongolia/3/2005 (H5N1) clade 2.2	A/Vietnam/1194/2004 (H5N1) clade 1	A/duck/Hokkaido/Vac-01/2004 (H5N1) classical clade	A/duck/Potsdam/1402-6/1986 (H5N2) classical clade	A/teal/Foehr/Wv1378-79/2003 (H5N2) classical clade
45 (C)	D	D	D	S	S	S
71 (E)	I	L	I	L	L	L
83 (E)	A	I	A	D	D	D
86 (E)	S	A	V	I	I	V
94	N	N	D	D	D	D
124 (B)	D	D	S	D	D	N
129	S	S	L	S	S	S
138 (A)	Q	Q	Q	N	N	N
140 (A)	R	R	K	R	R	R
155 (B)	S	N	S	N	N	S
156	A	A	T	A	A	A
174	V	V	V	V	I	V
181	P	P	P	P	P	P
183	D	D	D	D	D	D
189 (B)	R	R	K	K	K	K
212 (D)	K	K	R	E	E	E
227	E	E	E	E	E	E
263 (E)	A	T	T	T	T	T
269	L	L	L	L	L	L
277	K	K	K	K	K	K
282 (C)	M	I	M	M	M	M

^aNumbering according to the mature H5 hemagglutinin.

^bEMBL/GenBank accession numbers: A/chicken/Yamaguchi/7/2004 (GU186708), A/whooper swan/3/2005 (BAE48316), A/Vietnam/1194/2004 (ABP51976), A/duck/Hokkaido/Vac-01/2004 (AB259712), A/duck/Potsdam/1402-6/1986 (AAD13574), A/teal/Foehr/Wv1378-79/2003 (HF563058).