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GABAB receptors mediate the reduction produced by baclofen. A: Time course showing the reduction and increase in failure rate of evoked EPSCs by bath application of 5 μM baclofen and the reversal of baclofen’s effect by co-application of 100 μM CGP 35348 in a P12 interneuron. B: Average EPSCs corresponding to the average of 10 traces taken at the times indicated in A. C: The average EPSC expressed as a percent of the control EPSC in 4 cells. * p < 0.05.
