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. Author manuscript; available in PMC: 2013 Jun 10.
Published in final edited form as: Clin Sci (Lond). 2011 Nov;121(10):427–436. doi: 10.1042/CS20110153

Figure 1. Maternal antioxidant therapy attenuates conditioned fear and blocks the programming effects of CBX.

Figure 1

One day after training mice to associate a specific context with an aversive stimulus, they were returned to the conditioned context. Fearful behaviour (time spent freezing) was measured in adult offspring of dams that received either saline (solid bars) or CBX (open bars) during pregnancy. n = 13 male saline, n = 10 male CBX, n = 6 male saline–tempol, n = 6 male CBX–tempol, n = 14 female saline, n = 5 female CBX, n = 5 female saline–tempol, n = 4 female CBX–tempol. *P < 0.05 CBX compared with saline; †P < 0.01 tempol compared with no tempol.