Mean blood pressure (MBP, A), heart rate (HR, B) and relative locomotor activity (C) were assessed in adult offspring of dams that were either undisturbed during pregnancy (black bars) or received daily third trimester injections of saline (grey bars) or CBX (open bars). These baseline recordings were obtained every 5 min for 60 h. n = 6 male undisturbed, n = 6 male saline, n = 6 male CBX, n = 5 male undisturbed–tempol, n = 6 male saline–tempol, n = 8 male CBX–tempol, n = 12 female saline (n = 6 weaned to a hypercaloric diet), n = 12 female CBX (n = 6 weaned to a hypercaloric diet); †P < 0.05 CBX–tempol compared with CBX–water.